Looking east at the Los Santos Skyline

Downtown is a neighborhood in North Los Santos and the city's Central Business District. This is a district, known for its city's tallest buildings. Downtown of Los Santos, sits north of Pershing Square, the location of city's municipal government(where LSPD HQ and Los Santos City Hall located). Here goes the LSIA-Las Venturas highway, which connects Los Santos International Airport with Las Venturas.

The zip code of Downtown is 90021.